Description
产品说明
| 所属分类 | 细胞库 > 细胞系 > 人源 |
|---|---|
| 品牌 / 来源 | CS-BIC | 中科生信 |
| 最近更新 | 2026-10-26 |
| 别称 | UCH-1; UCH1 |
| 形态 | 间充质细胞样 |
| 疾病 | 脊索瘤 |
| 种属 | 人 |
| 产品使用 | 仅限于科学研究 ，不可作为动物或人类疾病的治疗产品使用。 |
| 保藏机构 | ATCC; CRL-3217 |
| 倍增时间 | 每周 2 至 3 次 |
| 冻存条件 | 冻存液：90%FBS ，DMSO 10% |
| 培养条件 | 气相：空气 ，95% ；二氧化碳 ，5%。 温度：37摄氏度 ，培养箱湿度为70%-80%。 |
| 生长特征 | 贴壁生长 |
| 组织来源 | 脊柱；骶骨 |
| 背景描述 | U-CH1 is the first human chordoma cell line. It exhibits chordoma-like characteristics and has molecular, genetic, and morphological features typical of chordoma. This cell line was established from a local recurrence of a sacrococcygeal chordoma after radiotherapy 4 years after initial surgery. Chordoma is a rare slow-growing tumor type, and U-CH1 is a relatively slow-growing cell line. U-CH1 has a heterogeneous morphology consisting of physaliferous cells with mcinous intercellular substance, which represent typical chordoma features. The cells overexpress the transcription factor T (Brachyury) that is the most specific marker for chordoma. This cell line was accessioned with the support of the Chordoma Foundation, a non-profit organization working to improve the lives of chordoma patients by accelerating research to develop effective treatments for the chordoma disease. |
| 完全培养基配置 | 70.4% IMDM+17.6% RPMI 1640+10%胎牛血清；1%双抗+1%谷氨酰胺 |
| 传代比例/细胞消化 | 1:2传代 ，消化2-3分钟 |
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